Tetanus toxin Rabbit Polyclonal Antibody (QYA10777)
產品名稱：破傷風毒素兔多克隆抗體
貨號：QYA10777
主要參數
應用：WB
適應物種：Tetanus toxin
同種型：IgG
儲存溫度：-20℃
建議工作濃度：WB:1:2000-5000
特異性：抗體可以檢測內源性和重組破傷風毒素蛋白
背景
破傷風毒素通過抑制神經遞質釋放發揮作用。它結合外周神經元突觸，經內化后通過逆向運輸沿軸突進入脊髓，并可在突觸后與突觸前神經元之間轉移。該毒素通過鋅內肽酶活性催化突觸短蛋白-2（synaptobrevin-2）第76位谷氨酰胺與第77位苯丙氨酸之間的鍵水解，從而抑制神經遞質釋放。
注：本產品僅用于科研用途，不用于診斷和治療。
Product name: Tetanus toxin Rabbit Polyclonal Antibody
Cat: QYA10777
Main parameter
Applications: WB
Reactivity: Tetanus toxin
Isotype: IgG
Storage: -20℃
Recommended dilutions: WB:1:2000-5000
Specificity: Antibody can detects endogenous and recombinant Tetanus toxin protein.
Background
Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.
P.s. This product is only used for scientific research, not for diagnosis and treatment.
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